Novel alleles in the era of next-generation sequencing-based HLA typing calls for standardization and policy

Novel alleles in the era of next-generation sequencing-based HLA typing calls for standardization and policy

Next-Generation Sequencing (NGS) has transformed clinical histocompatibility laboratories through its capacity to provide accurate, high-throughput, high-resolution typing of Human Leukocyte Antigen (HLA) genes, which is critical for transplant safety and success. As this technology becomes widely u...

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Bibliographic Details
Main Authors: Jenny N. Tran, Karen R. Sherwood, Ahmed Mostafa, Rey Vincent Benedicto, Allaa ElaAlim, Anna Greenshields, Paul Keown, Robert Liwski, James H. Lan
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Genetics
Subjects:
next-generation sequencing
HLA
novel alleles
standardization
proficiency testing
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2023.1282834/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2023.1282834/full

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