Neonatal loss of FGFR2 in astroglial cells affects locomotion, sociability, working memory, and glia-neuron interactions in mice

Neonatal loss of FGFR2 in astroglial cells affects locomotion, sociability, working memory, and glia-neuron interactions in mice

Abstract Fibroblast growth factor receptor 2 (FGFR2) is almost exclusively expressed in glial cells in postnatal mouse brain, but its impact in glia for brain behavioral functioning is poorly understood. We compared behavioral effects from FGFR2 loss in both neurons and astroglial cells and from FGF...

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Bibliographic Details
Main Authors: Hanna E. Stevens, Soraya Scuderi, Sarah C. Collica, Simone Tomasi, Tamas L. Horvath, Flora M. Vaccarino
Format: Article
Language:English
Published: Nature Publishing Group 2023-03-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-023-02372-y

Internet

https://doi.org/10.1038/s41398-023-02372-y

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