Pigment Epithelium-Derived Factor and Sex Hormone-Responsive Cancers

Oestrogens and androgens play important roles in normal and cancerous tissue and have been shown to negatively regulate pigment epithelium-derived factor (PEDF) expression in sex hormone-responsive tumours. PEDF suppresses tumour growth and its downregulation by oestrogen is implicated in tumorigene...

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Bibliographic Details
Main Authors: Naomi Brook, Emily Brook, Crispin R. Dass, Arlene Chan, Arun Dharmarajan
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/12/11/3483