Independent associations between arterial bicarbonate, apnea severity and hypertension in obstructive sleep apnea

Independent associations between arterial bicarbonate, apnea severity and hypertension in obstructive sleep apnea

Abstract Background Obstructive sleep apnea is characterized by intermittent hypoxia and hypercapnia. CO2 production, transport and elimination are influenced by the carbonic anhydrase enzyme. We hypothesized that elevated standard bicarbonate, a proxy for increased carbonic anhydrase activity, is a...

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Bibliographic Details
Main Authors: Davoud Eskandari, Ding Zou, Ludger Grote, Hartmut Schneider, Thomas Penzel, Jan Hedner
Format: Article
Language:English
Published: BMC 2017-06-01
Series:Respiratory Research
Subjects:
Acid base
Blood pressure
Carbonic anhydrase
Hypercapnia
Obstructive sleep apnea
Online Access:http://link.springer.com/article/10.1186/s12931-017-0607-9

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http://link.springer.com/article/10.1186/s12931-017-0607-9

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