Polo-like Kinase 4: A Multifaceted Marker Linking Tumor Aggressiveness and Unfavorable Prognosis, and Insights into Therapeutic Strategies

Polo-like Kinase 4: A Multifaceted Marker Linking Tumor Aggressiveness and Unfavorable Prognosis, and Insights into Therapeutic Strategies

(1) Background: This study investigated whether polo-like kinase 4 (PLK4) is a suitable therapeutic target or biomarker for lung adenocarcinoma (LUAD). (2) Methods: We acquired LUAD data from The Cancer Genome Atlas (TCGA) database through the UCSC Xena data portal. Gene expression, clinical, surviv...

Full description

Bibliographic Details
Main Authors: Youngtaek Kim, Joon Yeon Hwang, Dong Kwon Kim, Kwangmin Na, Seul Lee, Sujeong Baek, Seong-san Kang, Seung Min Yang, Mi Hyun Kim, Heekyung Han, Chai Young Lee, Yu Jin Han, Min Hee Hong, Jii Bum Lee, Sun Min Lim, Byoung Chul Cho, Youngjoon Park, Kyoung-Ho Pyo
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Cancers
Subjects:
lung adenocarcinoma
PLK4
<i>TP53</i>
biomarkers
drug resistance
Online Access:https://www.mdpi.com/2072-6694/15/18/4663

Internet

https://www.mdpi.com/2072-6694/15/18/4663

Similar Items