Differential hexosamine biosynthetic pathway gene expression with type 2 diabetes

Differential hexosamine biosynthetic pathway gene expression with type 2 diabetes

The hexosamine biosynthetic pathway (HBP) culminates in the attachment of O-linked β-N-acetylglucosamine (O-GlcNAc) onto serine/threonine residues of target proteins. The HBP is regulated by several modulators, i.e. O-linked β-N-acetylglucosaminyl transferase (OGT) and β-N-acetylglucosaminidase (OGA...

Full description

Bibliographic Details
Main Authors: Megan Coomer, M. Faadiel Essop
Format: Article
Language:English
Published: Elsevier 2014-01-01
Series:Molecular Genetics and Metabolism Reports
Subjects:
Hexosamine biosynthetic pathway
Fasting blood glucose
Pre- and overt diabetes
Leukocytes
Gene expression
Online Access:http://www.sciencedirect.com/science/article/pii/S2214426914000263

Internet

http://www.sciencedirect.com/science/article/pii/S2214426914000263

Similar Items