Protective Effects and Mechanisms of Esculetin against H<sub>2</sub>O<sub>2</sub>-Induced Oxidative Stress, Apoptosis, and Pyroptosis in Human Hepatoma HepG2 Cells

Protective Effects and Mechanisms of Esculetin against H<sub>2</sub>O<sub>2</sub>-Induced Oxidative Stress, Apoptosis, and Pyroptosis in Human Hepatoma HepG2 Cells

Oxidative stress plays a crucial role in the pathogenesis of many diseases. Esculetin is a natural coumarin compound with good antioxidant and anti-inflammatory properties. However, whether esculetin can protect HepG2 cells through inhibiting H<sub>2</sub>O<sub>2</sub>-induce...

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Bibliographic Details
Main Authors: Ying Luo, Tenglong Chang, Shiting Huang, Jing Xiang, Shuangyang Tang, Haiyan Shen
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Molecules
Subjects:
esculetin
oxidative stress
apoptosis
pyroptosis
JNK
liver diseases
Online Access:https://www.mdpi.com/1420-3049/29/7/1415

Internet

https://www.mdpi.com/1420-3049/29/7/1415

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