Structure and transport mechanism of the sodium/proton antiporter MjNhaP1

Structure and transport mechanism of the sodium/proton antiporter MjNhaP1

Sodium/proton antiporters are essential for sodium and pH homeostasis and play a major role in human health and disease. We determined the structures of the archaeal sodium/proton antiporter MjNhaP1 in two complementary states. The inward-open state was obtained by x-ray crystallography in the prese...

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Bibliographic Details
Main Authors: Cristina Paulino, David Wöhlert, Ekaterina Kapotova, Özkan Yildiz, Werner Kühlbrandt
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2014-11-01
Series:eLife
Subjects:
Methanocaldococcus jannaschii
membrane transport
sodium/proton antiport
electron cryo-microscopy
x-ray crystallography
transport mechanism
Online Access:https://elifesciences.org/articles/03583

Internet

https://elifesciences.org/articles/03583

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