Evaluation of the effect of carnosine, its novel derivative trolox-carnosine and trolox in a pre-clinical study focussing on the regulation of immunity

The neuroprotective or neurotoxic effects of the products of the kynurenine pathway of tryptophan metabolism highly depend on the action of kynurenine-3-monooxygenase (KMO). The present results show increased concentrations of the KMO in the plasma of rats repeatedly exposed to an immune challenge....

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Bibliographic Details
Main Authors: Slovák L., Poništ S., Kuncírová V., Mihalová D., Fedorova T., Bauerová K.
Format: Article
Language:English
Published: Sciendo 2016-09-01
Series:European Pharmaceutical Journal
Subjects:
Online Access:https://doi.org/10.1515/afpuc-2016-0001