RNA cancer vaccines: developing mRNA nanovaccine with self-adjuvant property for cancer immunotherapy

Messenger RNA (mRNA)-based cancer vaccine has become a popular approach for developing personalized and effective antitumor immunotherapy. To achieve robust antitumor efficacy, mRNA-encoding tumor antigens needs to be efficiently delivered and translated in dendritic cells for efficient antigen pres...

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Bibliographic Details
Main Authors: Hongxia Zhang, Xiaojun Xia
Format: Article
Language:English
Published: Taylor & Francis Group 2021-09-01
Series:Human Vaccines & Immunotherapeutics
Subjects:
Online Access:http://dx.doi.org/10.1080/21645515.2021.1921524