Translational toxicoepigenetic Meta-Analyses identify homologous gene DNA methylation reprogramming following developmental phthalate and lead exposure in mouse and human offspring

Translational toxicoepigenetic Meta-Analyses identify homologous gene DNA methylation reprogramming following developmental phthalate and lead exposure in mouse and human offspring

Although toxicology uses animal models to represent real-world human health scenarios, a critical translational gap between laboratory-based studies and epidemiology remains. In this study, we aimed to understand the toxicoepigenetic effects on DNA methylation after developmental exposure to two com...

Full description

Bibliographic Details
Main Authors: Rebekah L. Petroff, Dana C. Dolinoy, Kai Wang, Luke Montrose, Vasantha Padmanabhan, Karen E. Peterson, Douglas M. Ruden, Maureen A. Sartor, Laurie K. Svoboda, Martha M. Téllez-Rojo, Jaclyn M. Goodrich
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:Environment International
Subjects:
DNA methylation
DEHP
Lead (Pb)
Developmental exposures
Translational toxicology
Epigenetics
Online Access:http://www.sciencedirect.com/science/article/pii/S0160412024001612

Internet

http://www.sciencedirect.com/science/article/pii/S0160412024001612

Similar Items