Aryl hydrocarbon receptor and IL-13 signaling crosstalk in human keratinocytes and atopic dermatitis

Aryl hydrocarbon receptor and IL-13 signaling crosstalk in human keratinocytes and atopic dermatitis

IntroductionAtopic dermatitis (AD) is an allergic skin disease mediated by skin barrier impairment and IL-13-driven immune response. Activation of the aryl hydrocarbon receptor (AHR) has shown promise in early clinical trials for AD; however, the mechanism by which AHR partially ameliorates AD is no...

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Bibliographic Details
Main Authors: Steven P. Proper, Alexander T. Dwyer, Andrews Appiagyei, Jennifer M. Felton, Netali Ben-Baruch Morgenstern, Justin M. Marlman, Michael Kotliar, Artem Barski, Ty D. Troutman, Marc E. Rothenberg, Tesfaye B. Mersha, Nurit P. Azouz
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Allergy
Subjects:
aryl hydrocarbon receptor
keratinocytes
atopic dermatitis
IL-13
STAT6
tapinarof
Online Access:https://www.frontiersin.org/articles/10.3389/falgy.2024.1323405/full

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https://www.frontiersin.org/articles/10.3389/falgy.2024.1323405/full

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