Genome-wide genotype-serum proteome mapping provides insights into the cross-ancestry differences in cardiometabolic disease susceptibility

Genome-wide genotype-serum proteome mapping provides insights into the cross-ancestry differences in cardiometabolic disease susceptibility

Integrating genetic information with circulating proteomics can help understand mechanisms of disease. Here, the authors conduct genome-wide association analyses of the serum proteome in 2,958 Han Chinese individuals, uncovering proteins which may contribute to ancestry differences in cardiometaboli...

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Bibliographic Details
Main Authors: Fengzhe Xu, Evan Yi-Wen Yu, Xue Cai, Liang Yue, Li-peng Jing, Xinxiu Liang, Yuanqing Fu, Zelei Miao, Min Yang, Menglei Shuai, Wanglong Gou, Congmei Xiao, Zhangzhi Xue, Yuting Xie, Sainan Li, Sha Lu, Meiqi Shi, Xuhong Wang, Wensheng Hu, Claudia Langenberg, Jian Yang, Yu-ming Chen, Tiannan Guo, Ju-Sheng Zheng
Format: Article
Language:English
Published: Nature Portfolio 2023-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-36491-3

Internet

https://doi.org/10.1038/s41467-023-36491-3

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