Assessing organ-level immunoreactivity in a rat model of sepsis using TSPO PET imaging

Assessing organ-level immunoreactivity in a rat model of sepsis using TSPO PET imaging

There is current need for new approaches to assess/measure organ-level immunoreactivity and ensuing dysfunction in systemic inflammatory response syndrome (SIRS) and sepsis, in order to protect or recover organ function. Using a rat model of systemic sterile inflammatory shock (intravenous LPS admin...

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Bibliographic Details
Main Authors: Neysha Martinez-Orengo, Sarine Tahmazian, Jianhao Lai, Zeping Wang, Sanhita Sinharay, William Schreiber-Stainthorp, Falguni Basuli, Dragan Maric, William Reid, Swati Shah, Dima A. Hammoud
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Immunology
Subjects:
sepsis
TSPO (18 kda translocator protein)
18F-DPA-714
whole body PET/CT
organ-level immunoreactivity
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1010263/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2022.1010263/full

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