TME-targeted approaches of brain metastases and its clinical therapeutic evidence

TME-targeted approaches of brain metastases and its clinical therapeutic evidence

The tumor microenvironment (TME), which includes both cellular and non-cellular elements, is now recognized as one of the major regulators of the development of primary tumors, the metastasis of which occurs to specific organs, and the response to therapy. Development of immunotherapy and targeted t...

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Bibliographic Details
Main Authors: Ibrar Muhammad Khan, Safir Ullah Khan, Hari Siva Sai Sala, Munir Ullah Khan, Muhammad Azhar Ud Din, Samiullah Khan, Syed Shams ul Hassan, Nazir Muhammad Khan, Yong Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Immunology
Subjects:
brain metastases
tumor microenvironment
central nervous system barrier
immunotherapy
molecular mechanism
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1131874/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1131874/full

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