Harnessing adenovirus in cancer immunotherapy: evoking cellular immunity and targeting delivery in cell-specific manner

Abstract Recombinant adenovirus (rAd) regimens, including replication-competent oncolytic adenovirus (OAV) and replication-deficient adenovirus, have been identified as potential cancer therapeutics. OAV presents advantages such as selective replication, oncolytic efficacy, and tumor microenvironmen...

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Bibliographic Details
Main Authors: Miao Zeng, Wei Zhang, Yisheng Li, Li Yu
Format: Article
Language:English
Published: BMC 2024-03-01
Series:Biomarker Research
Subjects:
Online Access:https://doi.org/10.1186/s40364-024-00581-1