Interleukin-4 Programmed Macrophages Suppress Colitis and Do Not Enhance Infectious-Colitis, Inflammation-Associated Colon Cancer or Airway Hypersensitivity

Interleukin-4 Programmed Macrophages Suppress Colitis and Do Not Enhance Infectious-Colitis, Inflammation-Associated Colon Cancer or Airway Hypersensitivity

The murine interleukin-4 treated macrophage (MIL4) exerts anti-inflammatory and pro-healing effects and has been shown to reduce the severity of chemical-induced colitis. Positing M(IL4) transfer as an anti-inflammatory therapy, the possibility of side-effects must be considered. Consequently, bone...

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Bibliographic Details
Main Authors: Blanca E. Callejas, Graham A. D. Blyth, Nicholas Jendzjowsky, Arthur Wang, Anshu Babbar, Konstantin Koro, Richard J. A. Wilson, Margaret M. Kelly, Eduardo R. Cobo, Derek M. McKay
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Immunology
Subjects:
intestinal inflammation
macrophage-based therapy
colitis-associated colorectal cancer
Citrobacter rodentium
airway inflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.744738/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.744738/full

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