Utilizing in silico and in vitro methods to identify possible binding sites of a novel ligand against Pseudomonas aeruginosa phospholipase toxin ExoU

Utilizing in silico and in vitro methods to identify possible binding sites of a novel ligand against Pseudomonas aeruginosa phospholipase toxin ExoU

Multi-drug resistant infections caused by the opportunistic pathogen, Pseudomonas aeruginosa (P. aeruginosa), are a continuing problem that contribute to morbidity and mortality in immunocompromised hosts such as cystic fibrosis (CF), wound and burn patients. The bacterial toxin ExoU is one of four...

Full description

Bibliographic Details
Main Authors: Krista Chamberlain, Mya Johnson, Terry-Elinor Reid, Tzvia I. Springer
Format: Article
Language:English
Published: Elsevier 2022-03-01
Series:Biochemistry and Biophysics Reports
Subjects:
Phospholipase
ExoU
Saturation transfer nuclear magnetic resonance
Pseudomonas aeruginosa
Online Access:http://www.sciencedirect.com/science/article/pii/S240558082100282X

Internet

http://www.sciencedirect.com/science/article/pii/S240558082100282X

Similar Items