A multicenter cluster randomized, stepped wedge implementation trial for targeted normoxia in critically ill trauma patients: study protocol and statistical analysis plan for the Strategy to Avoid Excessive Oxygen (SAVE-O2) trial

A multicenter cluster randomized, stepped wedge implementation trial for targeted normoxia in critically ill trauma patients: study protocol and statistical analysis plan for the Strategy to Avoid Excessive Oxygen (SAVE-O2) trial

Abstract Background Targeted normoxia (SpO2 90–96% or PaO2 60–100 mmHg) may help to conserve oxygen and improve outcomes in critically ill patients by avoiding potentially harmful hyperoxia. However, the role of normoxia for critically ill trauma patients remains uncertain. The objective of this stu...

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Bibliographic Details
Main Authors: Layne Dylla, David J. Douin, Erin L. Anderson, John D. Rice, Conner L. Jackson, Vikhyat S. Bebarta, Christopher J. Lindsell, Alex C. Cheng, Steven G. Schauer, Adit A. Ginde
Format: Article
Language:English
Published: BMC 2021-11-01
Series:Trials
Subjects:
Oxygenation
Hyperoxia
Trauma
Injuries
Critical care
Intensive care units
Online Access:https://doi.org/10.1186/s13063-021-05688-6

Internet

https://doi.org/10.1186/s13063-021-05688-6

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