Isoliquiritigenin attenuates high-fat diet-induced intestinal damage by suppressing inflammation and oxidative stress and through activating Nrf2

Isoliquiritigenin attenuates high-fat diet-induced intestinal damage by suppressing inflammation and oxidative stress and through activating Nrf2

This study examined if isoliquiritigenin (ISL) attenuates high-fat diet (HFD)-induced intestinal damage and if this involves modulating Nrf2. Rats included 5 groups (n = 8/group): control (vehicle), ISL, HFD, HFD + ISL, and HFD + ISL + brusatol (an inhibitor of Nrf2). Treatments with the vehicle and...

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Bibliographic Details
Main Authors: Mohammed Abdo Yahya, Ghedeir M. Alshammari, Magdi A. Osman, Laila Naif Al-Harbi, Abu ElGasim A. Yagoub, Sahar Abdulaziz AlSedairy
Format: Article
Language:English
Published: Elsevier 2022-05-01
Series:Journal of Functional Foods
Subjects:
HFD
Intestine
Inflammation
Oxidative stress
Colitis
Nrf2
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464622001281

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http://www.sciencedirect.com/science/article/pii/S1756464622001281

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