Intragenic L1 Insertion: One Possibility of Brain Disorder

Long interspersed nuclear element 1 (LINE1, L1) is a retrotransposon comprising ~17% of the human genome. A subset of L1s maintains the potential to mobilize and alter the genomic landscape, consequently contributing to the change in genome integrity and gene expression. L1 retrotransposition occurs...

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Bibliographic Details
Main Authors: Ji-Hoon Son, Hyunsu Do, Jinju Han
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Life
Subjects:
Online Access:https://www.mdpi.com/2075-1729/12/9/1425