Intragenic L1 Insertion: One Possibility of Brain Disorder
Long interspersed nuclear element 1 (LINE1, L1) is a retrotransposon comprising ~17% of the human genome. A subset of L1s maintains the potential to mobilize and alter the genomic landscape, consequently contributing to the change in genome integrity and gene expression. L1 retrotransposition occurs...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-09-01
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Series: | Life |
Subjects: | |
Online Access: | https://www.mdpi.com/2075-1729/12/9/1425 |