Multiple receptor-ligand interactions direct tissue resident gamma delta T cell activation

Gamma delta T cells represent a major T cell population in epithelial tissues, such as skin, intestine, and lung, where they function in maintenance of the epithelium and provide a crucial first line defense against environmental and pathogenic insults. Despite their importance, the molecular mecha...

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Bibliographic Details
Main Authors: Deborah A. Witherden, Kevin eRamirez, Wendy L. Havran
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-11-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00602/full