Semisynthesis of 5-O-ester derivatives of renieramycin T and their cytotoxicity against non-small-cell lung cancer cell lines

Semisynthesis of 5-O-ester derivatives of renieramycin T and their cytotoxicity against non-small-cell lung cancer cell lines

Abstract The semisynthesis of 5-O-ester derivatives of renieramycin T was accomplished through the photoredox reaction of renieramycin M (1), a bistetrahydroisoquinolinequinone alkaloid isolated from the Thai blue sponge Xestospongia sp. This process led to the conversion of compound 1 to renieramyc...

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Main Authors: Koonchira Buaban, Bhurichaya Innets, Korrakod Petsri, Suwimon Sinsook, Pithi Chanvorachote, Chaisak Chansriniyom, Khanit Suwanborirux, Masashi Yokoya, Naoki Saito, Supakarn Chamni
Format: Article
Language:English
Published: Nature Portfolio 2023-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-48526-2

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https://doi.org/10.1038/s41598-023-48526-2

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