Development and use of a high-throughput screen to identify novel modulators of the corticotropin releasing factor binding protein
Background: Stress responses are believed to involve corticotropin releasing factor (CRF), its two cognate receptors (CRF1 and CRF2), and the CRF-binding protein (CRFBP). Whereas decades of research has focused on CRF1, the role of CRF2 in the central nervous system (CNS) has not been thoroughly inv...
Main Authors: | , , , , , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2022-12-01
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Series: | SLAS Discovery |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S247255522213697X |