Propagation of seminal toxins through binary expression gene drives could suppress populations

Abstract Gene drives can be highly effective in controlling a target population by disrupting a female fertility gene. To spread across a population, these drives require that disrupted alleles be largely recessive so as not to impose too high of a fitness penalty. We argue that this restriction may...

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Bibliographic Details
Main Authors: Juan Hurtado, Santiago Revale, Luciano M. Matzkin
Format: Article
Language:English
Published: Nature Portfolio 2022-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-10327-4