A COMPARATIVE STUDY OF METHODS OF THE SALICYLIC ACID CHLORINATION FOR FURTHER PRODUCTION OF ANTIHELMINTHIC DRUGS

With the help of thin-layer and high-performance liquid chromatography, the change in the composition of the reaction mass during the chlorination of salicylic acid was studied by three methods: molecular chlorine in acetic acid, sodium hypochlorite in an aqueous alkaline solution and oxidative chlo...

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Bibliographic Details
Main Authors: V. G. Dudarev, M. R. Kuzminykh, G. M. Alekseeva
Format: Article
Language:Russian
Published: LLC Center of Pharmaceutical Analytics (LLC «CPHA») 2019-01-01
Series:Разработка и регистрация лекарственных средств
Subjects:
Online Access:https://www.pharmjournal.ru/jour/article/view/610