Versatile approach towards fully desymmetrized trehalose with a novel set of orthogonal protecting groups

Versatile approach towards fully desymmetrized trehalose with a novel set of orthogonal protecting groups

Trehalose-containing glycans play an essential role in bacterial pathogenesis, host-pathogen interaction, and cell signaling. The investigation of trehalose uptake and metabolism in Mycobacteria using synthetic desymmetrized trehalose probes is an important approach for the development of diagnostic...

Full description

Bibliographic Details
Main Authors: Tomáš Vašíček, Benjamin Arensmeyer, Alessandro Monti, Alla Zamyatina
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Chemistry
Subjects:
carbohydrates
glycochemistry
synthesis
protecting group manipulations
regioselectivity
Online Access:https://www.frontiersin.org/articles/10.3389/fchem.2023.1332837/full

Internet

https://www.frontiersin.org/articles/10.3389/fchem.2023.1332837/full

Similar Items