RiboA: a web application to identify ribosome A-site locations in ribosome profiling data

Abstract Background Translation is a fundamental process in gene expression. Ribosome profiling is a method that enables the study of transcriptome-wide translation. A fundamental, technical challenge in analyzing Ribo-Seq data is identifying the A-site location on ribosome-protected mRNA fragments....

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Bibliographic Details
Main Authors: Danying Shao, Nabeel Ahmed, Nishant Soni, Edward P. O’Brien
Format: Article
Language:English
Published: BMC 2021-03-01
Series:BMC Bioinformatics
Subjects:
Online Access:https://doi.org/10.1186/s12859-021-04068-w