Activating the Cpx response induces tolerance to antisense PNA delivered by an arginine-rich peptide in Escherichia coli

Activating the Cpx response induces tolerance to antisense PNA delivered by an arginine-rich peptide in Escherichia coli

Cell-penetrating peptides (CPPs) are increasingly used for cellular drug delivery in both pro- and eukaryotic cells, and oligoarginines have attracted special attention. How arginine-rich CPPs translocate across the cell envelope, particularly for prokaryotes, is still unknown. Arginine-rich CPPs ef...

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Bibliographic Details
Main Authors: Jakob Frimodt-Møller, Andreas Koulouktsis, Godefroid Charbon, Marit Otterlei, Peter E. Nielsen, Anders Løbner-Olesen
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
peptide nucleic acids
Cpx response
aminoglycosides
arginine-rich cell-penetrating peptides
inner membrane
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253121001505

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http://www.sciencedirect.com/science/article/pii/S2162253121001505

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