The murine meninges acquire lymphoid tissue properties and harbour autoreactive B cells during chronic Trypanosoma brucei infection.

The meningeal space is a critical brain structure providing immunosurveillance for the central nervous system (CNS), but the impact of infections on the meningeal immune landscape is far from being fully understood. The extracellular protozoan parasite Trypanosoma brucei, which causes human African...

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Bibliographic Details
Main Authors: Juan F Quintana, Matthew C Sinton, Praveena Chandrasegaran, Lalit Kumar Dubey, John Ogunsola, Moumen Al Samman, Michael Haley, Gail McConnell, Nono-Raymond Kuispond Swar, Dieudonné Mumba Ngoyi, David Bending, Luis de Lecea, Annette MacLeod, Neil A Mabbott
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-11-01
Series:PLoS Biology
Online Access:https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.3002389&type=printable