Bacterial Production of Recombinant Coagulation Factor VIII Domains

Factor VIII (F8) is a blood coagulation protein prearranged in six domains, and its deficiency causes hemophilia A. To fashion functional F8 therapeutics, development of a recombinant F8 (rF8) domain is essential not only for F8 substitution, but also to decipher the F8-related mechanisms. In this s...

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Bibliographic Details
Main Authors: Saima Bashar, Hee-Jin Jeong
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Medicina
Subjects:
Online Access:https://www.mdpi.com/1648-9144/59/4/694