Bacterial Production of Recombinant Coagulation Factor VIII Domains
Factor VIII (F8) is a blood coagulation protein prearranged in six domains, and its deficiency causes hemophilia A. To fashion functional F8 therapeutics, development of a recombinant F8 (rF8) domain is essential not only for F8 substitution, but also to decipher the F8-related mechanisms. In this s...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-04-01
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Series: | Medicina |
Subjects: | |
Online Access: | https://www.mdpi.com/1648-9144/59/4/694 |