PRL1 Promotes Glioblastoma Invasion and Tumorigenesis via Activating USP36-Mediated Snail2 Deubiquitination

PRL1 Promotes Glioblastoma Invasion and Tumorigenesis via Activating USP36-Mediated Snail2 Deubiquitination

Regenerating liver phosphatase 1 (PRL1) is an established oncogene in various cancers, although its biological function and the underlying mechanisms in glioblastoma multiforme (GBM) remain unclear. Here, we showed that PRL1 was significantly upregulated in glioma tissues and cell lines, and positiv...

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Bibliographic Details
Main Authors: Wenjin Qiu, Xiaomin Cai, Kaya Xu, Shibin Song, Zumu Xiao, Yunan Hou, Xiaolan Qi, Feng Liu, Yimin Chen, Hua Yang, Liangzhao Chu, Jian Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Oncology
Subjects:
glioblastoma
PRL1
epithelial mesenchymal transition
Snail2
deubiquitination
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.795633/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.795633/full

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