Kinome-Wide siRNA Screening Identifies DYRK1B as a Potential Therapeutic Target for Triple-Negative Breast Cancer Cells

Kinome-Wide siRNA Screening Identifies DYRK1B as a Potential Therapeutic Target for Triple-Negative Breast Cancer Cells

Aims: The selective molecules for targeted therapy of triple-negative breast cancer (TNBC) are limited. Several kinases play pivotal roles in cancer development and malignancy. The study aims to determine if any kinases confer to malignancy of TNBC cells, which could serve as a theranostic target fo...

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Bibliographic Details
Main Authors: Chia-Che Chang, Chien-Chih Chiu, Pei-Feng Liu, Chih-Hsuan Wu, Yen-Chiang Tseng, Cheng-Hsin Lee, Chih-Wen Shu
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Cancers
Subjects:
kinome
siRNA
screening
DYRK1B
prognosis
triple-negative breast cancer
Online Access:https://www.mdpi.com/2072-6694/13/22/5779

Internet

https://www.mdpi.com/2072-6694/13/22/5779

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