Translational neurophysiological biomarkers of N-methyl-d-aspartate receptor dysfunction in serine racemase knockout mice

Alterations in glutamatergic function are well established in schizophrenia (Sz), but new treatment development is hampered by the lack of translational pathophysiological and target engagement biomarkers as well as by the lack of animal models that recapitulate the pathophysiological features of Sz...

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Bibliographic Details
Main Authors: Andrea Balla, Stephen Ginsberg, Atheir I. Abbas, Henry Sershen, Daniel C. Javitt
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:Biomarkers in Neuropsychiatry
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666144620300095