Nanopore adaptive sampling effectively enriches bacterial plasmids

ABSTRACTBacterial plasmids play a major role in the spread of antibiotic resistance genes. However, their characterization via DNA sequencing suffers from the low abundance of plasmid DNA in those samples. Although sample preparation methods can enrich the proportion of plasmid DNA before sequencing...

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Bibliographic Details
Main Authors: Jens-Uwe Ulrich, Lennard Epping, Tanja Pilz, Birgit Walther, Kerstin Stingl, Torsten Semmler, Bernhard Y. Renard
Format: Article
Language:English
Published: American Society for Microbiology 2024-03-01
Series:mSystems
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/msystems.00945-23