Granzyme K initiates IL-6 and IL-8 release from epithelial cells by activating protease-activated receptor 2.

Granzyme K (GzmK) is a tryptic member of the granzyme family of chymotrypsin-like serine proteases produced by cells of the immune system. Previous studies have indicated that GzmK activates protease-activated receptor 1 (PAR1) enhancing activation of monocytes and wound healing in endothelial cells...

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Main Authors: Dion Kaiserman, Peishen Zhao, Caitlin Lorraine Rowe, Andrea Leong, Nicholas Barlow, Lars Thomas Joeckel, Corinne Hitchen, Sarah Elizabeth Stewart, Morley D Hollenberg, Nigel Bunnett, Andreas Suhrbier, Phillip Ian Bird
פורמט: Article
שפה:English
יצא לאור: Public Library of Science (PLoS) 2022-01-01
סדרה:PLoS ONE
גישה מקוונת:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0270584&type=printable