Restoring mitochondrial cardiolipin homeostasis reduces cell death and promotes recovery after spinal cord injury

Abstract Alterations in phospholipids have long been associated with spinal cord injury (SCI). However, their specific roles and signaling cascades in mediating cell death and tissue repair remain unclear. Here we investigated whether alterations of cardiolipin (CL), a family of mitochondrion-specif...

Full description

Bibliographic Details
Main Authors: Nai-Kui Liu, Ling-Xiao Deng, Miao Wang, Qing-Bo Lu, Chunyan Wang, Xiangbing Wu, Wei Wu, Ying Wang, Wenrui Qu, Qi Han, Yongzhi Xia, Baylen Ravenscraft, Jin-Lian Li, Si-Wei You, Peter Wipf, Xianlin Han, Xiao-Ming Xu
Format: Article
Language:English
Published: Nature Publishing Group 2022-12-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-022-05369-5