miR-132 regulates the expression of synaptic proteins in APP/PS1 transgenic mice through C1q
Cognitive impairment in Alzheimer’s disease (AD) is usually accompanied by synaptic loss in both the hippocampus and neocortex. In the early stage of AD, amyloid β-induced synapse changes is the main reason, while in the later stage, the accumulation of Tau protein promotes synapse degeneration as t...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
PAGEPress Publications
2019-05-01
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Series: | European Journal of Histochemistry |
Subjects: | |
Online Access: | https://ejh.it/index.php/ejh/article/view/3008 |