miR-132 regulates the expression of synaptic proteins in APP/PS1 transgenic mice through C1q

miR-132 regulates the expression of synaptic proteins in APP/PS1 transgenic mice through C1q

Cognitive impairment in Alzheimer’s disease (AD) is usually accompanied by synaptic loss in both the hippocampus and neocortex. In the early stage of AD, amyloid β-induced synapse changes is the main reason, while in the later stage, the accumulation of Tau protein promotes synapse degeneration as t...

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Bibliographic Details
Main Authors: Nan Xu, Ang-Di Li, Li-Li Ji, Yao Ye, Zhen-Yu Wang, Lei Tong
Format: Article
Language:English
Published: PAGEPress Publications 2019-05-01
Series:European Journal of Histochemistry
Subjects:
miR-132
Alzheimer's disease
synapse
C1q
Online Access:https://ejh.it/index.php/ejh/article/view/3008

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