Trabectedin may be a valuable treatment option for elderly patients with metastatic soft tissue sarcomas

Trabectedin may be a valuable treatment option for elderly patients with metastatic soft tissue sarcomas

BackgroundIn the landscape of metastatic soft tissue sarcoma (mSTS) treatment, anthracyclines have shown efficacy; however, their associated toxicity imposes significant limitations, especially in frail elderly patients with mSTS who are highly susceptible to severe adverse effects. In this context,...

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Bibliographic Details
Main Authors: Gianmaria Miolo, Angela Buonadonna, Davide Lombardi, Simona Scalone, Andrea Lauretta, Lara Della Puppa, Giuseppe Corona
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-07-01
Series:Frontiers in Oncology
Subjects:
cancer
trabectedin
elderly
sarcoma
first-line treatment
pharmacokinetics
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2024.1437732/full

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https://www.frontiersin.org/articles/10.3389/fonc.2024.1437732/full

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