Glutathione Metabolism Is a Regulator of the Acute Inflammatory Response of Monocytes to (1→3)-β-D-Glucan

Glutathione Metabolism Is a Regulator of the Acute Inflammatory Response of Monocytes to (1→3)-β-D-Glucan

(1→3)-β-D-Glucan (BDG) represents a potent pathogen-associated molecular pattern (PAMP) in triggering the host response to fungal and some bacterial infections. Monocytes play a key role in recognizing BDG and governing the acute host response to infections. However, the mechanisms regulating monocy...

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Bibliographic Details
Main Authors: Rayoun Ramendra, Mathieu Mancini, Jose-Mauricio Ayala, Lin Tze Tung, Stephane Isnard, John Lin, Jean-Pierre Routy, Anastasia Nijnik, David Langlais
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Immunology
Subjects:
B-glucan
glutathione
immunometabolism
innate immunity
host response
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.694152/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.694152/full

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