Isofuranodiene, a Natural Sesquiterpene Isolated from Wild Celery (<i>Smyrnium olusatrum</i> L.), Protects Rats against Acute Ischemic Stroke

Isofuranodiene, a Natural Sesquiterpene Isolated from Wild Celery (<i>Smyrnium olusatrum</i> L.), Protects Rats against Acute Ischemic Stroke

The myrrh-like furanosesquiterpene isofuranodiene (IFD) is the main constituent of wild celery (<i>Smyrnium olusatrum</i> L., Apiaceae), an overlooked vegetable that was cultivated during the Roman Empire. In the present study, we investigated the protective effects of IFD pre-treatment...

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Bibliographic Details
Main Authors: Hasan Yousefi-Manesh, Ahmad Reza Dehpour, Samira Shirooie, Fariba Bagheri, Vida Farrokhi, Seyyedeh Elaheh Mousavi, Massimo Ricciutelli, Loredana Cappellacci, Víctor López, Filippo Maggi, Riccardo Petrelli
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Pharmaceuticals
Subjects:
isofuranodiene
<i>Smyrnium olusatrum</i> L.
ischemic stroke
NF-ĸB
IL-1β
TNF-α
Online Access:https://www.mdpi.com/1424-8247/14/4/344

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https://www.mdpi.com/1424-8247/14/4/344

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