A radiomics signature derived from CT imaging to predict MSI status and immunotherapy outcomes in gastric cancer: a multi-cohort study

A radiomics signature derived from CT imaging to predict MSI status and immunotherapy outcomes in gastric cancer: a multi-cohort study

Abstract Background Accurate microsatellite instability (MSI) testing is essential for identifying gastric cancer (GC) patients eligible for immunotherapy. We aimed to develop and validate a CT-based radiomics signature to predict MSI and immunotherapy outcomes in GC. Methods This retrospective mult...

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Bibliographic Details
Main Authors: Peng-chao Zhan, Shuo Yang, Xing Liu, Yu-yuan Zhang, Rui Wang, Jia-xing Wang, Qing-ya Qiu, Yu Gao, Dong-bo Lv, Li-ming Li, Cheng-long Luo, Zhi-wei Hu, Zhen Li, Pei-jie Lyu, Pan Liang, Jian-bo Gao
Format: Article
Language:English
Published: BMC 2024-04-01
Series:BMC Cancer
Subjects:
Gastric cancer
MSI
Immunotherapy
Radiomics signature
mRNA-seq
Online Access:https://doi.org/10.1186/s12885-024-12174-0

Internet

https://doi.org/10.1186/s12885-024-12174-0

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