“It’s Only a Model”: When Protein Structure Predictions Need Experimental Validation, the Case of the HTLV-1 Tax Protein

Human T-cell Leukemia Virus type 1 (HTLV-1) is a human retrovirus responsible for leukaemia in 5 to 10% of infected individuals. Among the viral proteins, Tax has been described as directly involved in virus-induced leukemogenesis. Tax is therefore an interesting therapeutic target. However, its 3D...

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Bibliographic Details
Main Authors: Christophe Guillon, Xavier Robert, Patrice Gouet
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Pathogens
Subjects:
Online Access:https://www.mdpi.com/2076-0817/13/3/241