Importance of CD8 T cell-mediated immune response during intracellular parasitic infections and its implications for the development of effective vaccines

Importance of CD8 T cell-mediated immune response during intracellular parasitic infections and its implications for the development of effective vaccines

Obligatory intracellular parasites such as Plasmodium sp, Trypanosoma cruzi, Toxoplasma gondii and Leishmania sp are responsible for the infection of hundreds of millions of individuals every year. These parasites can deliver antigens to the host cell cytoplasm that are presented through MHC class I...

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Bibliographic Details
Main Authors: Rodrigues Mauricio M., Boscardin Silvia B., Vasconcelos José R., Hiyane Meire I., Salay Gerson, Soares Irene S.
Format: Article
Language:English
Published: Academia Brasileira de Ciências 2003-01-01
Series:Anais da Academia Brasileira de Ciências
Subjects:
CD8
parasites
immunity
vaccine
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652003000400005

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652003000400005

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