AID/APOBEC cytosine deaminase induces genome-wide kataegis
<p>Abstract</p> <p>Clusters of localized hypermutation in human breast cancer genomes, named “kataegis” (from the Greek for thunderstorm), are hypothesized to result from multiple cytosine deaminations catalyzed by AID/APOBEC proteins. However, a direct link between APOBECs and kat...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2012-12-01
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| Series: | Biology Direct |
| Subjects: | |
| Online Access: | http://www.biology-direct.com/content/7/1/47 |