SLAMF7 regulates the inflammatory response in macrophages during polymicrobial sepsis

Uncontrolled inflammation occurred in sepsis results in multiple organ injuries and shock, which contributes to the death of patients with sepsis. However, the regulatory mechanisms that restrict excessive inflammation are still elusive. Here, we identified an Ig-like receptor called signaling lymph...

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Bibliographic Details
Main Authors: Yongjian Wu, Qiaohua Wang, Miao Li, Juanfeng Lao, Huishu Tang, Siqi Ming, Minhao Wu, Sitang Gong, Linhai Li, Lei Liu, Xi Huang
Format: Article
Language:English
Published: American Society for Clinical Investigation 2023-03-01
Series:The Journal of Clinical Investigation
Subjects:
Online Access:https://doi.org/10.1172/JCI150224