Dysregulation of Nrf2 in Hepatocellular Carcinoma: Role in Cancer Progression and Chemoresistance

The liver executes versatile functions and is the chief organ for metabolism of toxicants/xenobiotics. Hepatocellular carcinoma (HCC) is the most common primary liver malignancy and the third foremost cause of cancer death worldwide. Oxidative stress is a key factor related with the development and...

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Bibliographic Details
Main Authors: Azhwar Raghunath, Kiruthika Sundarraj, Frank Arfuso, Gautam Sethi, Ekambaram Perumal
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/10/12/481