T-bet+ Memory B Cells Link to Local Cross-Reactive IgG upon Human Rhinovirus Infection

T-bet+ Memory B Cells Link to Local Cross-Reactive IgG upon Human Rhinovirus Infection

Summary: Human rhinoviruses cause the common cold and exacerbate chronic respiratory diseases. Although infection elicits neutralizing antibodies, these do not persist or cross-protect across multiple rhinovirus strains. To analyze rhinovirus-specific B cell responses in humans, we developed techniq...

Full description

Bibliographic Details
Main Authors: Jacob D. Eccles, Ronald B. Turner, Nicole A. Kirk, Lyndsey M. Muehling, Larry Borish, John W. Steinke, Spencer C. Payne, Paul W. Wright, Deborah Thacker, Sampo J. Lahtinen, Markus J. Lehtinen, Peter W. Heymann, Judith A. Woodfolk
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719316778

Internet

http://www.sciencedirect.com/science/article/pii/S2211124719316778

Similar Items